New York City Health Department Issues Health Advisory on First Mpox Clade I Case Detected in the City

Risk to the Public Remains Low

No Additional Known Cases of Mpox Clade I in the Five Boroughs

March 13, 2026 — The New York City Health Department today issued a Health Advisory to health care providers about a travel-related mpox clade I case detected in New York City. This is the first known mpox clade I case in New York City. The person who tested positive for mpox clade I recently traveled internationally.

“There is no known local transmission of mpox clade I in New York City and the risk remains low for New Yorkers,” said NYC Health Commissioner Dr. Alister Martin. “The NYC Health Department recommends that New Yorkers who are at risk for mpox receive and complete the two-dose vaccine series that works to prevent mpox.”

Mpox Vaccine

Vaccination reduces your risk of getting mpox and can reduce symptoms if you do get it. People at risk for mpox should get 2 doses of the JYNNEOS vaccine if they have not already done so to maximize protection. The second dose should be administered at least 28 days after the first dose. If you’ve already had mpox, you do not need to get vaccinated.

Who Should Get Vaccinated

Talk to your provider about vaccination if:

  • You have sex with men and identify as male, trans, nonbinary, genderqueer or gender non-conforming.
  • You are planning to visit a country where clade I mpox virus is spreading and you anticipate sex with a new partner while traveling, regardless of your sexual orientation or gender identity.
  • You consider yourself to be at risk for mpox through sex or other intimate contact now or in the future. Learn more about how mpox spreads.

If you have recently been in close contact with someone you think has mpox, you should get the vaccine as soon as possible and no later than 14 days after the exposure.

To find a vaccination site, visit the NYC Health Map or call 311.

For more information about mpox, including prevention, symptoms, diagnosis, and care, visit NYC Health: Mpox.

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MEDIA CONTACT: PressOffice@health.nyc.gov