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Toxicology Technical Manuals
Standard Operating Procedures Manual Cover Page
Management and Administration
The Forensic Toxicology Laboratory Mission Statement
Access to the Forensic Toxicology Laboratory
Standard Operating Procedures Manual
Analytical Testing Guidelines (Post Mortem)
Analytical Testing Guidelines (Human Performance)
Routinely Tested Analytes
Case Information and Results
Final Toxicology Report
Confidentiality of Case Information and Results
Personnel Training Criteria
Continuing Education
Continuing Education Annual Submission Form
Notification Guidelines in Cases of Laboratory Error or Misconduct by Laboratory Personnel
Scientific Working Group for Forensic Toxicology (SWGTOX) – Standard for Developing a Guide and Code of Professional Conduct in Forensic Toxicology
Specimen Management
Post Mortem (OCME) Specimens
Human Performance (Non OCME) Specimens
Computer Assisted Toxicology Specimen Discard – Post Mortem Specimens
Specimen Send Out to Reference Laboratory Guidelines
Quality Assurance and Quality Control
Quality Assurance and Quality Control
Quality Control Summary
Calibration Curves
Method Validation
Method Validation Criteria
Data Review and Reporting
Proficiency Testing
American Board of Forensic Toxicology (ABFT) - Guidelines for Performing Corrective Action for Deviations in Proficiency Test Results
Proficiency Survey Corrective Action Form
Pipette Calibration Procedure
Scientific Working Group for Forensic Toxicology (SWGTOX) – Standard Practices for Method Validation in Forensic Toxicology
Internal Audit Procedure
Non-Conforming Work Procedure
Immunoassays
Screening for Drugs of Abuse in Urine, Whole Blood, Serum and Vitreous Humor by Enzyme-Linked Immunosorbent Assay on the Dynex DSX Microtitter Plate Analyzer
Preparation of Quality Control for Enzyme-Linked Immunosorbent Assay in Whole Blood, Serum and Vitreous Humor
Preparation of Quality Control for Enzyme-Linked Immunosorbent Assay in Urine
Head Space Gas Chromatography
Ethanol, Methanol, 2-Propanol and Acetone by Automated Head Space Analysis
Volatiles Analysis by GCMS Head Space Analysis
Analysis of Miscellaneous Volatile Compounds by Head Space Chromatography
Comprehensive Screening by GCMS and NPD
Basic Drugs Screening by Gas Chromatography / Mass Spectrometry
Gas Chromatography Mass Spectrometry
Sympathomimetic Amines by Solid Phase Extraction and Gas Chromatography / Mass Spectrometry (Full Scan)
Sympathomimetic Amines by Solid Phase Extraction and Gas Chromatography / Mass Spectrometry (Selective Ion Monitoring)
Benzodiazepines by Solid Phase Extraction and Gas Chromatography / Mass Spectrometry (Selected Ion Monitoring)
Carisoprodol, Meporobamate, Topiramate by Solid Phase Extraction and Gas Chromatography / Mass Spectrometry (Selected Ion Monitoring)
Fentanyl by Solid Phase Extraction and Gas Chromatography / Mass Spectrometry (Selected Ion Monitoring)
Gamma-Hydroxybutyrate by Solid Phase Extraction and Gas Chromatography / Mass Spectrometry (Selected Ion Monitoring)
Ehylene Glycol and Propylene Glycol by Gas Chromatography / Mass Spectrometry
Nicotine and Cotinine by Solid Phase Extraction and Gas Chromatography / Mass Spectrometry (Selected Ion Monitoring)
Cocaine, Ethylbenzoylecgonine, Benzoylecgonine, Codeine, 6-MAM and Morphine by Gas Chromatography / Mass Spectrometry
Hydrolysis Specimens for Solid Phase Extraction
GC / Mass Spectrometry Tuning (Autotune)
GC / MS Maintenance
Tramadol, O-desmethyltramadol, N-desmethyltramadol by Solid Phase Extraction with GCMS/NPD Analysis
Levetiracetam by Solid Phase Extraction and Gas Chromatography/Mass Spectrometry (Selective Ion Monitoring)
Methadone & EDDP by Liquid/Liquid Extraction and Gas Chromatography/Mass Spectrometry (Selective Ion Monitoring)
Gas Chromatography NPD
Basic Drugs Quantitation by NPD Gas Chromatography
Basic Analytes Calibrators and Controls
Cyanide by NPD Gas Chromatography
GC-NPD Derivatives with TFAA
NPD Gas Chromatography
Drugs Extracted by SPE with GC-NPD Analysis (Lamotrigine, Ondansetron, Cetirizine, Clonidine, Clopidogrel)
Metoclopramide, Trimethoprim, Ticlopidine, Tramadol, Tramadol Metabolites (O-Desmethyl and N-Desmethyl Tramadol), Bromazepam, Venlafaxine and O-Desmethyl Venlafaxine by SPE and GC-NPD Analysis
GC Routine Maintenance Agilent 6890
Troubleshooting of Agilent Gas Chromatographs
High Performance Liquid Chromatography
Acetaminophen, Salicylates, Theophylline, Caffeine by Solid Phase Extraction and High Performance Liquid Chromatography
Barbiturates, Phenytoin and Carbamazepine by Solid Phase Extraction and High Performance Liquid Chromatography
Ibuprofen, Naproxen, Warfarin by High Performance Liquid Chromatography
Ibuprofen, Naproxen, Warfarin by Solid Phase Extraction and High Performance Liquid Chromatography
Preparation of Quality Control for HPLC Assays
HPLC Sequence Set Up using Easy Sequence
HPLC Maintenance
HPLC Troubleshooting
Liquid Chromatography Gas Spectrometry
Benzoylecgonine, Cocaine, EBE, Morphine, Codeine, 6-MAM, Oxycodone, Ocymorphone, Hydrocodone and Hydromorphone by LCMS Analysis
LCMS Tuning (Autotime / Checktune)
Miscellaneous Procedures
Acetaminophen (Color Test)
Salicylates (Color Test)
Preparation of Quality Control for Color Tests
Ethchlorvynol (Color Test)
Halogen Hydrocarbons (Color Test)
Cyanide (Color Test)
Carbon Monoxide by Microdiffusion (qualitative)
Heavy Metals Antimony, Arsenic, Bismuth, Mercury by Reinsch Test
Vitreous Humor Chemistries
7-aminoclonazepam, Clonazepam (Panel 1) by Solid Phase Extraction and Liquid Chromatography/Mass Spectrometry (Selected Ion Monitoring) in Blood or Serum
Nordiazepam (Panel 2) by Solid Phase Extraction and Liquid Chromatography/Mass Spectrometry (Selected Ion Monitoring) in Blood or Serum
Clenbuterol by Liquid Chromatography/Mass Spectrometry
Spectrophotometry
Carbon Monoxide by AVOXimeter 4000 CO-Oximeter
AVOXimeter 4000 CO-Oximeter Maintenance
Carboxyhemoglobin Saturation by Spectrophotometry
Trichloroethanol (TCE) by Spectrophotometry
UV-Visible Spectrophotometer Agilent 8453 Routine Maintenance