City to Adopt New Intradermal Monkeypox Vaccination Strategy to Reach More New Yorkers

New strategy follows federal direction on intradermal administration

City will make more than 12,000 new first-dose public appointments available at 6PM on Wednesday, August 24, at and by calling 877-VAX-4NYC (877-829-4692)

More doses available will allow for second dose availability to be shared within the next week

August 23, 2022 — New York City has announced that it will adopt the new intradermal monkeypox vaccination strategy mandated by the federal government, which will expand available dose supply with which to vaccinate more New Yorkers. Tomorrow night, more than 12,000 new first-dose public appointments will be made available.

“As we continue to see a scarcity of federal supply of monkeypox vaccines, we must adapt to provide a range of options to those who are vaccine-eligible, and to do so in an equitable way,” said Health Commissioner Dr. Ashwin Vasan. “The Health Department is working to balance these considerations and the concerns we’ve heard from community advocates under supply constraints. We have met with leaders, heard their recommendations, and are committed to working through these challenges so that we can follow federal mandates, while still fulfilling our obligation to reach every New Yorker who needs a vaccine.”

Earlier this month, the U.S. Food and Drug Administration (FDA) issued an emergency use authorization that allows health care providers to administer the monkeypox vaccine intradermally to eligible individuals, aged 18 years and older. The federal government has since mandated intradermal administration as part of its National Monkeypox Vaccination Strategy. Intradermal administration of the JYNNEOSTM vaccine can yield roughly four to five times the number of doses per vial than the subcutaneous method of administration, and deliver the same immune response, based on the data available.

During this transition, the Health Department will continue to work with providers and community partners to route eligible New Yorkers to vaccine appointments and provide guidance on the best methods of administration for their patients. The city has begun training vaccinators and will continue to work with health care providers on preparation for broader-scale intradermal administration. The city will also continue to deepen its engagement with community partners to inform its response, improve vaccine confidence, and address questions about the change to administration method so that all New Yorkers can make informed choices about protecting themselves and their communities during this outbreak.

On Wednesday, August 24, more than 12,000 first-dose public appointments will be made available on the city’s vaccine portal: and by calling 877-VAX-4NYC (877-829-4692). These appointments will take place from August 25th through September 3rd. Additional appointments will continue to be made available through community-based organizations, providers serving New Yorkers within prioritized populations at elevated risk of infection, and through direct enrollment at community events; some of these appointments will continue to be for doses administered via subcutaneous injection for the next several weeks.

With more doses available for New Yorkers, information about second dose availability will be shared within the next week.

As more New Yorkers are diagnosed with monkeypox, it is crucial to seek care as soon as a rash or sore is identified. New Yorkers should call their health care provider immediately. For those who do not have one, they can call 311 to get connected to an NYC Health + Hospitals location or to access H+H Virtual Express Care. New Yorkers can also visit the NYC Health Map to find a nearby provider. Care is available in New York City regardless of immigration status, insurance coverage, or ability to pay. To learn more, visit our Monkekypox page.



MEDIA CONTACT: Patrick Gallahue/Victoria Merlino,